Use of Psychedelic Drug Psilocybin (Magic Mushrooms) Associated With Lower Risk of Opioid Addiction

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Psilocybin Mushrooms

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Psilocybin mushrooms

Adults who have at a long time in their life utilized psilocybin– a psychedelic compound produced by some kinds of mushrooms– are 30% less most likely to have opioid usage condition, according to a nationally representative study of United States grownups reported in the journal Scientific Reports

Psilocybin mushrooms; typically referred to as magic mushrooms or shrooms, are a group of fungis which contain psilocybin which becomes psilocin upon consumption. Psilocybin is a naturally happening psychedelic prodrug substance, which implies it is a biologically non-active substance that the body transforms into a drug.

Grant Jones and associates examined the occurrence of opioid usage condition and the occurrence of psychedelic usage amongst 214,505 grownups utilizing study information gathered in between 2015 and2019 Participants reported whether they had actually abused or experienced reliance on heroin or prescription painkiller in the previous year and reported whether they had actually ever taken the hallucinogens psilocybin, peyote, mescaline, or LSD. 2,183 (1.0%) individuals satisfied the requirements for opioid usage condition in the previous year. 22,276 (104%) individuals reported having actually utilized psilocybin and 10,284 (46%) of those likewise reported utilizing heroin or prescription painkiller recreationally a minimum of as soon as in their lives.

The scientists discovered that opioid usage condition was 30% less most likely amongst those had actually utilized psilocybin, compared to those who had actually never ever utilized it. Those who utilized psilocybin were likewise in between 17% and 34% less most likely to have actually experienced 7 of the 11 signs of opioid reliance and abuse in the previous year, compared to those who had actually never ever utilized it. This recommends that psilocybin usage might have a protective result versus a series of opioid usage condition signs. The scientists did not determine considerable associations in between peyote, mescaline or LSD usage and the probability of opioid usage condition.

The authors hypothesize that psilocybin might safeguard versus opioid usage condition by impacting the transmission of serotonin and dopamine– neurotransmitters that previous research study has actually discovered are connected with dependency. Additionally, they recommend that the magical or spiritual experiences that psilocybin causes might reduce the probability of users establishing opioid usage condition as previous research studies have actually observed associations in between spiritual experiences and beliefs and favorable drug abuse healing results. Further research study, consisting of long-lasting observational research studies and scientific trials, is required to examine the relationship in between psilocybin and opioid usage, they include.

Reference: “Associations between classic psychedelics and opioid use disorder in a nationally-representative U.S. adult sample” by Grant Jones, Jocelyn A. Ricard, Joshua Lipson and Matthew K. Nock, 7 April 2022, Scientific Reports
DOI: 10.1038/ s41598 -022-08085 -4