Analysis of Seroprevalence in Kenya Suggests COVID-19 Virus Exposure More Extensive Than Reported

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Researchers examining blood samples from blood donors throughout Kenya price quote that by June 2020, when numerous COVID-19 deaths were anticipated in the nation however hadn’t took place at such scale, 4.3% of Kenyans had antibodies to the infection. This recommends SARS-CoV-2 direct exposure has actually been more substantial than shown by case-based security in Kenya, the authors state.

Their outcomes will assist direct the pandemic action in an area where financial results of lockdown — consisting of for the method it interferes with regular healthcare to ladies and kids — have actually shown especially incapacitating. Africa represent 17% of the international population however by late July 2020, regardless of proof of numerous months of SARS-CoV-2 transmission, it represented just 5% of the international COVID-19 cases and 3% of the international COVID-19 deaths.

In Kenya, the very first case of SARS-CoV-2 was reported in mid-March 2020, followed rapidly by the organization of lockdowns. By end of July, nevertheless, nationwide security taped 20,636 cases and 341 deaths in Kenya — a boost especially slower than the epidemic in parts of China, Europe, and the United States.

Seeking to comprehend this pattern, Sophie Uyoga and associates carried out among the very first field-based seroprevalence studies in Africa. They examined samples gathered from more than 3,000 blood transfusion donors from late April to mid-June 2020. Using an extremely particular assay, the authors report an unrefined seroprevalence of 5.6% in this group. Adjusting for the age-sex structure of Kenya, the authors approximate a total seroprevalence of 4.3%, peaking in more youthful age, which follows other research studies.

The authors use numerous possible descriptions for why Kenya has actually seen reasonably lower cases and deaths even as SARS-CoV-2 direct exposure appears significant, consisting of the high group age-pyramid in Kenya, which leads to a smaller sized susceptible age. The outcomes of their research study, state the authors, assistance “the impression that disease may be attenuated in Africa.”

Reference: “Seroprevalence of anti–SARS-CoV-2 IgG antibodies in Kenyan blood donors” by Sophie Uyoga, Ifedayo M. O. Adetifa, Henry K. Karanja, James Nyagwange, James Tuju, Perpetual Wanjiku, Rashid Aman, Mercy Mwangangi, Patrick Amoth, Kadondi Kasera, Wangari Ng’ang’a, Charles Rombo, Christine Yegon, Khamisi Kithi, Elizabeth Odhiambo, Thomas Rotich, Irene Orgut, Sammy Kihara, Mark Otiende, Christian Bottomley, Zonia N. Mupe, Eunice W. Kagucia, Katherine E. Gallagher, Anthony Etyang, Shirine Voller, John N. Gitonga, Daisy Mugo, Charles N. Agoti, Edward Otieno, Leonard Ndwiga, Teresa Lambe, Daniel Wright, Edwine Barasa, Benjamin Tsofa, Philip Bejon, Lynette I. Ochola-Oyier, Ambrose Agweyu, J. Anthony G. Scott and George M. Warimwe, 11 November 2020, Science.
DOI: 10.1126/science.abe1916

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