Up to 3 cups of coffee daily is connected with a lower danger of stroke and deadly heart problem, according to research study provided at ESC Congress 2021. 1,2
“To our knowledge, this is the largest study to systematically assess the cardiovascular effects of regular coffee consumption in a population without diagnosed heart disease,” stated research study authorDr Judit Simon, of the Heart and Vascular Centre, Semmelweis University, Budapest, Hungary.
“Our results suggest that regular coffee consumption is safe, as even high daily intake was not associated with adverse cardiovascular outcomes and all-cause mortality after a follow-up of 10 to 15 years,” she continued. “Moreover, 0.5 to 3 cups of coffee per day was independently associated with lower risks of stroke, death from cardiovascular disease, and death from any cause.”
Even though coffee is amongst the most taken in drinks on the planet, little is learnt about the long-lasting effect of routine intake on cardiovascular health.
This research study examined the association in between normal coffee consumption and event cardiovascular disease, stroke, and death. The research study consisted of 468,629 individuals of the UK Biobank without any indications of heart problem at the time of recruitment. The typical age was 56.2 years and 55.8% were ladies.
Participants were divided into 3 groups according to their normal coffee consumption: none (did not take in coffee regularly, 22.1%), light-to-moderate (0.5 to 3 cups/day, 58.4%), and high (more than 3 cups/day, 19.5%).
The scientists approximated the association of day-to-day coffee intake with event results over an average follow-up of 11 years utilizing multivariable designs. The analyses were changed for aspects that might affect the relationship consisting of age, sex, weight, height, cigarette smoking status, exercise, hypertension, diabetes, cholesterol level, socioeconomic status, and normal consumption of alcohol, meat, tea, vegetables and fruit.
Compared to non-coffee drinkers, light-to-moderate intake was connected with a 12% lower danger of all-cause death (risk ratio [HR]= 0.88, p<< 0.001), 17% lower danger of death from heart disease (HR= 0.83, p= 0.006), and 21% lower danger of event stroke (HR= 0.79 ; p= 0.037).
To analyze the possible hidden systems, the scientists examined the association in between day-to-day coffee consumption and heart structure and function over an average follow-up of 11 years. For this, they utilized information from 30,650 individuals who went through heart magnetic resonance imaging (MRI), which is thought about the gold requirement for the evaluation of heart structure and function.
Dr Simon stated: “The imaging analysis indicated that compared with participants who did not drink coffee regularly, daily consumers had healthier sized and better functioning hearts. This was consistent with reversing the detrimental effects of aging on the heart.”
She concluded: “Our findings suggest that coffee consumption of up to 3 cups per day is associated with favorable cardiovascular outcomes. While further studies are needed to explain the underlying mechanisms, the observed benefits might be partly explained by positive alterations in cardiac structure and function.”
References and notes
- Abstract title: Association of day-to-day coffee intake with cardiovascular health– Results from the UK Biobank.
- Press conference: “Heart health made easy” on Thursday, August 26, from 17: 00 to 18: 00 CEST.
Funding: P.B.M and S.E.P acknowledge assistance from the National Institute for Health Research (NIHR) Barts Biomedical ResearchCentre S.E.P. acknowledges assistance from the ‘SmartHeart’ EPSRC program grant (www.nihr.ac.uk; EP/P001009/ 1) and likewise from the CAP-AI program, London’s very first AI allowing program concentrated on promoting development in the capital’s AISector CAP-AI is led by Capital Enterprise in collaboration with Barts Health NHS Trust and Digital Catapult and is moneyed by the European Regional Development Fund and BartsCharity S.E.P. and S.N. acknowledge the British Heart Foundation for moneying the manual analysis to develop a cardiovascular magnetic resonance imaging recommendation requirement for the UK Biobank imaging resource in 5000 CMR scans (www.bhf.org.uk; PG/14/89/31194). S.N and SKP supported by the Oxford NIHR Biomedical Research Centre and S.N. by the Oxford British Heart Foundation Centre of ResearchExcellence N.A. acknowledges the National Institute for Health Research (NIHR) Integrated Academic Training program which supports their Academic Clinical Lectureship posts. N.C.H acknowledges assistance from the UK Medical Research Council (MRC #405050259 and #U105960371), NIHR Southampton Biomedical Research Centre, University of Southampton, and University HospitalSouthampton Z.R.E was supported by a British Heart Foundation Clinical Research Training Fellowship (FS/17/81/33318). Project no. NVKP _16 -1–2016-0017 (‘National Heart Program’) has actually been executed with the assistance supplied from the National Research, Development and Innovation Fund of Hungary, funded under the NVKP _16 financing plan. The research study was funded by the Thematic Excellence Programme (2020 -4.1.1.- TKP2020) of the Ministry for Innovation and Technology in Hungary, within the structure of the Therapeutic Development and Bioimaging thematic programs of the Semmelweis University.
